The genetic mutation can occur when a person has a deficiency in the enzyme called cytochrome-b5 methemoglobin reductase, which is responsible for recessive congenital methemoglobinemia. They also lacked the enzyme diaphorase in their red blood cells, normally diaphorase converts methemoglobin back to hemoglobin.
Methemoglobinemia is a blood disorder in which an large amount of methemoglobin (a form of hemoglobin) is produced
Methemoglobin can develop blue skin without any negative symptoms.
Meet the Fulgates, a family of people with blue skin that lived in Kentucky for many generations. Most of the family members never suffered any health effects and lived into their 80s and 90s. It was discovered that there was inbreeding within the family that contributed to the high number of blue offspring.
Reality Decoded 
Interesting. Never knew about that. Who would have thought it was possible? We learn something new every day.
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The world gets stranger every day.
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Drinking too much SunnyD can cause your skin to turn yellow, …but that’s a temporary change, not permanent.
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Green women from Venus might be interesting to meet.
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This reminded me of an article I saw recently:
https://www.iflscience.com/health-and-medicine/too-much-toothache-medication-turned-this-womans-blood-blue/
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Wow!! That is very interesting, Thanks!
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Welcome.
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Tell me about it=)
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Anyone else think of Mystique?
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I did.
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And blue man group
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I had to google them (LOL).
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Dear Alex Sutton and J-M,
One of the episodes of the TV series called “9-1-1” depicts the fire rescue team coming to the aid of a lady who has turned blue:
Yours sincerely,
SoundEagle
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Wow!
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Interesting!
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Fascinating, I never heard about it. Nature can act in mysterious ways.
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💜 Why a “deficiency” EveryOne; maybe because I AM NOT White I Have a “deficiency”
…💛💚💙…
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